Arena Pharmaceuticals initiates individual screening for phase 1 clinical trial of APD916 Arena Pharmaceuticals, Inc. announced today the initiation of individual screening in a Stage 1 scientific trial of APD916, a novel oral drug candidate discovered by Arena that targets the histamine H3 receptor for the treating narcolepsy and cataplexy tadalafil-en-belgique.com . ‘There exists a dependence on better tolerated, far better therapies for narcolepsy, narcolepsy with cataplexy especially,’ stated William R. Shanahan, M.D., Arena’s Vice President and Chief Medical Officer. ‘Based on preclinical data, we believe that APD916 may substantially improve the treatment of the potential orphan indications.’ This randomized, double-blind and placebo-controlled Stage 1 trial is prepared to enroll up to 72 healthy adult volunteers and can evaluate the safety, tolerability and pharmacokinetics of single-ascending dosages of APD916..
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